- May 7: Mr. Satan becomes world champion.
- May 12: Goku becomes ill with the Heart Virus. Android 19 is killed by Vegeta and Dr. Gero is killed by Android 17.
- Between May 12 and May 16: Kami merges with Piccolo; the Nameless Namek returns into being.
- May 15: Goku finally recovers from his heart disease thanks to the Heart Medicine Future Trunks brought him from his time. He tells the others of the Hyperbolic Time Chamber, and Vegeta and Future Trunks enter it to train.
- May 16: Android 17 and Android 18 are absorbed by Cell.
- May 17: Cell announces the Cell Games to the entire World. Goku and Gohan exit the Hyperbolic Time Chamber, and Piccolo enters it.
- Cooler is killed when Vegeta crushes the Big Gete Star's core chip (movie only).
- Android 15 is killed (movie only).
- Android 14 is killed (movie only).
- Android 13 is killed (movie only).
- Paragus is crushed to death in his Attack Ball by Broly (movie only).
- Broly is defeated by Goku (movie only).
- Hatchiyack is killed (movie only).
- May 26: the Cell Games begin
- Android 16 is killed by Cell.
- Cell Juniors are created by Cell, and then killed by Super Saiyan 2 Gohan.
- Goku, King Kai, Bubbles, and Gregory are killed when Semi-Perfect Cell self destructs.
- Future Trunks is killed by Cell in his Super Perfect Form using the Full Power Death Beam.
- Cell is defeated and killed by Super Saiyan 2 Gohan.
- Android 17 is killed when Cell is killed, and is later revived.
- Bojack is killed by Gohan (movie only).
- Goten is born.
- Future Dr. Gero is killed by Future Android 17.
- May 12th: The Androids kill all of the Z Fighters except for Future Gohan and Future Trunks.
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